Assay Detail
Binding
CHEMBL5533400
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Flag-tagged BTK (unknown origin) expressed in HEK293T cells pre-incubated for 30 mins followed by ATP addition and measured after 20 mins by Western blotting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293T |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
MNK, mTOR or eIF4E-selecting the best anti-tumor target for blocking translation initiation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.03 | 8.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4075449 | — | — | 1 | 8.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4075449 | — | IC50 | = | 9.4 | nM | 8.03 |