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Assay Detail

CHEMBL5533902

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against mouse MEF cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type MEF
Confidence 1 — Organism
Curated By Autocuration

Target

MEF (CHEMBL614342)
Type CELL-LINE
Organism Mus musculus

Publication

Dual inhibitors of HDAC and other epigenetic regulators: A novel strategy for cancer treatment.
Shirbhate E, Singh V, Jahoriya V, Mishra A, Veerasamy R, Tiwari AK, Rajak H.
Eur J Med Chem (2024) 263 : 115938 -115938
PubMed 37989059 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.24 5.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3989941 TINOSTAMUSTINE 2.0 1 5.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3989941 TINOSTAMUSTINE IC50 = 5700.0 nM 5.24