Assay Detail
Functional
CHEMBL5534743
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Antibacterial activity against wild type Escherichia coli assessed as reduction in bacterial growth inhibition incubated for 24 hrs by broth microdilution method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Guiding the Way: Traditional Medicinal Chemistry Inspiration for Rational Gram-Negative Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.64 | 4.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5185676 | — | — | 1 | 4.64 |
| CHEMBL5173025 | — | — | 1 | 4.64 |
| CHEMBL5193767 | — | — | 1 | 4.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5185676 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL5173025 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL5193767 | — | IC50 | = | 23000.0 | nM | 4.64 |