Assay Detail
Binding
CHEMBL5536569
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NEK3 (unknown origin) in presence of ATP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase Nek3 (CHEMBL5679) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Potent, Selective, and Orally Bioavailable Quinazoline-Based STK17A/B Dual Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.61 | 6.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5575113 | — | — | 1 | 6.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5575113 | — | IC50 | = | 245.0 | nM | 6.61 |