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Assay Detail

CHEMBL5537533

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Hepatitis C virus genotype 2a NS5B polymerase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepacivirus hominis
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Hepatitis C virus NS5B RNA-dependent RNA polymerase (CHEMBL5375)
Type SINGLE PROTEIN
Organism Hepatitis C virus

Publication

Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.
Niu ZX, Nie P, Herdewijn P, Wang YT.
Eur J Med Chem (2023) 262 : 115919 -115919
PubMed 37922830 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3039514 ELBASVIR 4.0 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3039514 ELBASVIR EC50 = 3.0 nM 8.52