Assay Detail
Functional
CHEMBL5537679
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Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as reduction in TNF-alpha level incubated for 24 hrs by ELISA
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of cinnamoyl tethered indoline derivatives with anti-inflammatory and antioxidant activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.82 | 5.82 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5589744 | — | — | 2 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5589744 | — | IC50 | = | 1520.0 | nM | 5.82 |
| CHEMBL5589744 | — | Activity | - | — | - |