Assay Detail
Binding
CHEMBL5539883
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Hepatitis C virus genotype 2a NS5B polymerase assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepacivirus hominis |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Hepatitis C virus NS5B RNA-dependent RNA polymerase (CHEMBL5375) ↗| Type | SINGLE PROTEIN |
| Organism | Hepatitis C virus |
Publication
Hepatitis C: The Story of a Long Journey through First, Second, and Third Generation NS3/4A Peptidomimetic Inhibitors. What Did We Learn?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 10.28 | 10.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3545363 | GLECAPREVIR | 4.0 | 1 | 10.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3545363 | GLECAPREVIR | Ki | = | 0.053 | nM | 10.28 |