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Assay Detail

CHEMBL5540465

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitumor activity against human Leukemia cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Leukemia cell
Confidence 1 — Organism
Curated By Autocuration

Target

Leukemia cell (CHEMBL614844)
Type CELL-LINE
Organism Homo sapiens

Publication

Combination Therapy and Dual-Target Inhibitors Based on LSD1: New Emerging Tools in Cancer Therapy.
Shen L, Wang B, Wang SP, Ji SK, Fu MJ, Wang SW, Hou WQ, Dai XJ, Liu HM.
J Med Chem (2024) 67 : 922 -951
PubMed 38214982 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 10.00 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3781751 IADADEMSTAT 2.0 1 10.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3781751 IADADEMSTAT EC50 = 0.1 nM 10.00