Assay Detail
Binding
CHEMBL5541167
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HDAC7 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Multitargeting HDAC Inhibitors Containing a RAS/RAF Protein Interfering Unit.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.72 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5563252 | — | — | 1 | 6.92 |
| CHEMBL5563126 | — | — | 1 | 6.73 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 6.51 |
| CHEMBL1241855 | RIGOSERTIB | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5563252 | — | IC50 | = | 121.28 | nM | 6.92 |
| CHEMBL5563126 | — | IC50 | = | 184.36 | nM | 6.73 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 311.42 | nM | 6.51 |
| CHEMBL1241855 | RIGOSERTIB | IC50 | > | 10000.0 | nM | - |