Assay Detail
Functional
CHEMBL5543323
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Antiinflammatory activity against mouse RAW264.7 cells assessed as reduction of LPS-induced NO production
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of anti-inflammatory natural flavonoids: Diverse scaffolds and promising leads for drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.64 | 4.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 4.85 |
| CHEMBL456062 | — | — | 1 | 4.55 |
| CHEMBL465371 | KAZINOL B | — | 1 | 4.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | IC50 | = | 14160.0 | nM | 4.85 |
| CHEMBL456062 | — | IC50 | = | 28400.0 | nM | 4.55 |
| CHEMBL465371 | KAZINOL B | IC50 | = | 29310.0 | nM | 4.53 |