Assay Detail
Functional
CHEMBL5543447
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Antiproliferative activity against human cisplatin-resistant A2780 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780cisR |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances of antitumor leading compound Erianin: Mechanisms of action and structural modification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.59 | 9.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4458738 | — | — | 1 | 9.62 |
| CHEMBL5562521 | — | — | 1 | 9.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4458738 | — | IC50 | = | 0.24 | nM | 9.62 |
| CHEMBL5562521 | — | IC50 | = | 0.28 | nM | 9.55 |