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Assay Detail

CHEMBL5543533

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to iNOS (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Nitric oxide synthase, inducible (CHEMBL4481)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Advances in nitric oxide regulators for the treatment of ischemic stroke.
Wu J, Jia J, Ji D, Jiao W, Huang Z, Zhang Y.
Eur J Med Chem (2023) 262 : 115912 -115912
PubMed 37931330 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.80 4.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL225304 PIMAGEDINE 2.0 1 4.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL225304 PIMAGEDINE Ki = 16000.0 nM 4.80