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Assay Detail

CHEMBL5543535

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Binding
Binding affinity to human iNOS assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Nitric oxide synthase, inducible (CHEMBL4481)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Advances in nitric oxide regulators for the treatment of ischemic stroke.
Wu J, Jia J, Ji D, Jiao W, Huang Z, Zhang Y.
Eur J Med Chem (2023) 262 : 115912 -115912
PubMed 37931330 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.15 8.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL107251 1400W 1 8.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL107251 1400W Kd = 7.0 nM 8.15