Assay Detail
Binding
CHEMBL5544342
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Binding affinity to biotin-labeled c-myc DNA G-quadruplex (unknown origin) immobilized on SA biosensor assessed as dissociation constant by BLI assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Targeting G-rich sequence to regulate the transcription of murine double minute (MDM) genes in triple-negative breast cancers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 4.81 | 4.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5572579 | — | — | 1 | 4.81 |
| CHEMBL5573700 | — | — | 1 | - |
| CHEMBL5568951 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5572579 | — | Kd | = | 15600.0 | nM | 4.81 |
| CHEMBL5573700 | — | Kd | > | 25000.0 | nM | - |
| CHEMBL5568951 | — | Kd | > | 25000.0 | nM | - |