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Assay Detail

CHEMBL5548888

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human recombinant PREP expressed in Escherichia coli BL21 (DE3) cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prolyl endopeptidase (CHEMBL3202)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Druglike, <sup>18</sup>F-labeled PET Tracers Targeting Fibroblast Activation Protein.
Tanc M, Filippi N, Van Rymenant Y, Grintsevich S, Pintelon I, Verschuuren M, De Loose J, Verhulst E, Moon ES, Cianni L, Stroobants S, Augustyns K, Roesch F, De Meester I, Elvas F, Van der Veken P.
J Med Chem (2024) 67 : 7068 -7087
PubMed 38656144 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.75 5.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3233842 1 5.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3233842 IC50 = 1800.0 nM 5.75