Assay Detail
Binding
CHEMBL5550941
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to c-MYC G-quadruplex DNA (unknown origin) assessed as dissociation constant by fluorescence spectrophotometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Development of a fluorescent ligand that can illuminate nuclear G-quadruplexes and modulate oncogene expression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.16 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5438257 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5438257 | — | Kd | = | 700.0 | nM | 6.16 |