Assay Detail
Functional
CHEMBL5552311
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Antiproliferative activity against human U87 cells incubated for 72 hrs by alamar blue staining based analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-87MG ATCC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Comprehensive analysis of resorcinyl-imidazole Hsp90 inhibitor design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.31 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5569309 | — | — | 1 | 6.96 |
| CHEMBL5574581 | — | — | 1 | 6.72 |
| CHEMBL5562891 | — | — | 1 | 4.42 |
| CHEMBL5570148 | — | — | 1 | 4.36 |
| CHEMBL5566352 | — | — | 1 | 4.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5569309 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL5574581 | — | EC50 | = | 190.0 | nM | 6.72 |
| CHEMBL5562891 | — | EC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL5570148 | — | EC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL5566352 | — | EC50 | = | 81000.0 | nM | 4.09 |