Assay Detail
Functional
CHEMBL5554006
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Protection against CCl4-induced ferroptosis in mouse AML12 cells assessed as cell viability in presence of Ferrostatin-1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | AML12 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of a NCOA4 Degrader for Labile Iron-Dependent Ferroptosis Inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.05 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5571421 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5571421 | — | EC50 | = | 9.0 | nM | 8.05 |