Assay Detail
Functional
CHEMBL5576842
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV-1 infected in human MT4 cells assessed as inhibition of viral growth
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
The role of the methoxy group in approved drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.61 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL379664 | — | — | 1 | 7.12 |
| CHEMBL270717 | — | — | 1 | 6.09 |
| CHEMBL382680 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL379664 | — | EC50 | = | 76.3 | nM | 7.12 |
| CHEMBL270717 | — | EC50 | = | 805.2 | nM | 6.09 |
| CHEMBL382680 | — | EC50 | > | 30000.0 | nM | - |