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Assay Detail

CHEMBL5577617

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to prolidase (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Xaa-Pro dipeptidase (CHEMBL4185)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeting prolidase. A survey of the literature data to depict a structure-activity relationship frame and to address future studies for drug development.
Fiorito S, Collevecchio C, Epifano F, Genovese S.
Bioorg Med Chem (2024) 110 : 117833 -117833
PubMed 38996544 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.05 4.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL242863 1 4.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL242863 Ki = 90000.0 nM 4.05