Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5579019

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against mouse RAW264.7 cells incubated for 24 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Mus musculus
Cell Type RAW264.7
Confidence 1 — Organism
Curated By Autocuration

Target

RAW264.7 (CHEMBL612557)
Type CELL-LINE
Organism Mus musculus

Publication

Computational Design of Pore-Forming Peptides with Potent Antimicrobial and Anticancer Activities.
Deb R, Torres MDT, Boudný M, Koběrská M, Cappiello F, Popper M, Dvořáková Bendová K, Drabinová M, Hanáčková A, Jeannot K, Petřík M, Mangoni ML, Balíková Novotná G, Mráz M, de la Fuente-Nunez C, Vácha R.
J Med Chem (2024) 67 : 14040 -14061
PubMed 39116273 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.48 4.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5590247 1 4.60
CHEMBL5593337 1 4.51
CHEMBL5584167 1 4.44
CHEMBL5594579 1 4.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5590247 IC50 = 25000.0 nM 4.60
CHEMBL5593337 IC50 = 31000.0 nM 4.51
CHEMBL5584167 IC50 = 36000.0 nM 4.44
CHEMBL5594579 IC50 = 44000.0 nM 4.36