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Assay Detail

CHEMBL5579072

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-cancer activity against human MOLM-13 cells incubated for 24 hrs by WST assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MOLM-13
Confidence 1 — Organism
Curated By Autocuration

Target

MOLM-13 (CHEMBL3706572)
Type CELL-LINE
Organism Homo sapiens

Publication

Computational Design of Pore-Forming Peptides with Potent Antimicrobial and Anticancer Activities.
Deb R, Torres MDT, Boudný M, Koběrská M, Cappiello F, Popper M, Dvořáková Bendová K, Drabinová M, Hanáčková A, Jeannot K, Petřík M, Mangoni ML, Balíková Novotná G, Mráz M, de la Fuente-Nunez C, Vácha R.
J Med Chem (2024) 67 : 14040 -14061
PubMed 39116273 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5594932 1 6.00
CHEMBL5594579 1 -
CHEMBL412927 MELITTIN 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5594932 IC50 = 1000.0 nM 6.00
CHEMBL5594579 IC50 <= 10000.0 nM -
CHEMBL412927 MELITTIN IC50 <= 5000.0 nM -