Assay Detail
Binding
CHEMBL5579430
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of STT3A/STT3B mediated N-linked glycosylation in STT3A knockout human H1-HeLa cells stably transduced with Halo3N-ER sequence by measuring effective concentration incubated for 24 hrs by Western blotting analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | H1-HeLa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.41 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5584184 | — | — | 1 | 7.55 |
| CHEMBL5583722 | — | — | 1 | 7.47 |
| CHEMBL5591147 | — | — | 1 | 7.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5584184 | — | EC50 | = | 28.0 | nM | 7.55 |
| CHEMBL5583722 | — | EC50 | = | 34.0 | nM | 7.47 |
| CHEMBL5591147 | — | EC50 | = | 63.0 | nM | 7.20 |