Assay Detail
Binding
CHEMBL5579552
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activation of PKM2 (unknown origin) by LDH enzyme coupled assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeted suppression of oral squamous cell carcinoma by pyrimidine-tethered quinoxaline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.92 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5590652 | — | — | 1 | 9.22 |
| CHEMBL1090777 | — | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5590652 | — | EC50 | = | 0.6 | nM | 9.22 |
| CHEMBL1090777 | — | EC50 | = | 241.0 | nM | 6.62 |