Assay Detail
Binding
CHEMBL5580696
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Inhibition of human AChE by Ellman's method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
New insights into butyrylcholinesterase: Pharmaceutical applications, selective inhibitors and multitarget-directed ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.44 | 5.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5594849 | — | — | 1 | 5.84 |
| CHEMBL118752 | — | — | 1 | 5.36 |
| CHEMBL5592518 | — | — | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5594849 | — | IC50 | = | 1460.0 | nM | 5.84 |
| CHEMBL118752 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL5592518 | — | IC50 | = | 7530.0 | nM | 5.12 |