Assay Detail
Binding
CHEMBL5580722
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured for 60 mins by Ellman's method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
New insights into butyrylcholinesterase: Pharmaceutical applications, selective inhibitors and multitarget-directed ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1201196 | SERTACONAZOLE | 4.0 | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1201196 | SERTACONAZOLE | IC50 | = | 100.0 | nM | 7.00 |