Assay Detail
Binding
CHEMBL5580828
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant full length His-tagged CDK9/cyclin T1 extracted from Insect cells using biotinylated peptide biotin-Ttds-YISPLKSPYKISEG as substrate preincubated for 30 mins followed by substrate addition and measured for 60 mins by TR-FRET analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Insect cell |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Targeting cyclin-dependent kinases: From pocket specificity to drug selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.96 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4743691 | — | — | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4743691 | — | IC50 | = | 11.0 | nM | 7.96 |