Assay Detail

CHEMBL5581263

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Binding

Inhibition of FXa (unknown origin)

ChEMBL ↗

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Target

Coagulation factor X (CHEMBL244) ↗

Open DB target context

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Primary target Coagulation factor X

CHEMBL244

Anchored from Assay target.

Protein identity Coagulation factor X

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Coagulation factor X (CHEMBL244) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

The U.S. FDA approved cardiovascular drugs from 2011 to 2023: A medicinal chemistry perspective.

Jiang Y, Liu P, Qiu Z, Zhou M, Cheng M, Yang T.
Eur J Med Chem (2024) 275 : 116593 -116593
PubMed 38889609 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.68	8.68

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL198362	RIVAROXABAN	4.0	1	8.68

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL198362	RIVAROXABAN	IC50	=	2.1	nM	8.68