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Assay Detail

CHEMBL5581271

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to thrombin (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prothrombin (CHEMBL204)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The U.S. FDA approved cardiovascular drugs from 2011 to 2023: A medicinal chemistry perspective.
Jiang Y, Liu P, Qiu Z, Zhou M, Cheng M, Yang T.
Eur J Med Chem (2024) 275 : 116593 -116593
PubMed 38889609 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.22 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1269025 EDOXABAN 4.0 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1269025 EDOXABAN Ki = 6000.0 nM 5.22