Assay Detail
Functional
CHEMBL5582443
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Enhancement of HSP90 inhibitor AT13387-induced antiproliferative activity against human HCT-116 cells assessed as HSP90 inhibitor AT13387 IC50 at 50 uM incubated for 72 hrs by CCK8 assay (Rvb = 78.49 nM)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Allosteric Activation of Protein Phosphatase 5 with Small Molecules.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.39 | 7.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5593159 | — | — | 1 | 7.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5593159 | — | IC50 | = | 40.79 | nM | 7.39 |