Assay Detail
Binding
CHEMBL5582694
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to MDM2 (unknown origin) assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Cellular, Structural Basis, and Recent Progress for Targeting Murine Double Minute X (MDMX) in Tumors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.95 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL524251 | — | — | 1 | 5.00 |
| CHEMBL291426 | HINOKIFLAVONE | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL524251 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL291426 | HINOKIFLAVONE | Ki | = | 13000.0 | nM | 4.89 |