Assay Detail
Binding
CHEMBL5584804
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of AXL (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein kinase receptor UFO (CHEMBL4895) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent advances in c-Met-based dual inhibitors in the treatment of cancers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.89 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5597086 | — | — | 1 | 8.15 |
| CHEMBL5596801 | — | — | 1 | 8.07 |
| CHEMBL5598344 | — | — | 1 | 7.76 |
| CHEMBL5596908 | — | — | 1 | 7.58 |
| CHEMBL5598343 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5597086 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL5596801 | — | IC50 | = | 8.6 | nM | 8.07 |
| CHEMBL5598344 | — | IC50 | = | 17.2 | nM | 7.76 |
| CHEMBL5596908 | — | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL5598343 | — | IC50 | > | 1000.0 | nM | - |