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Assay Detail

CHEMBL5584934

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of AChE (unknown origin) using acetylcholineesterase as substrate assessed as inhibition constant by Lineweaver-Burk plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Acetylcholinesterase (CHEMBL220)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Exploring fluorine-substituted piperidines as potential therapeutics for diabetes mellitus and Alzheimer's diseases.
Mughal EU, Hawsawi MB, Naeem N, Hassan A, Alluhaibi MS, Ali Shah SW, Nazir Y, Sadiq A, Alrafai HA, Ahmed SA.
Eur J Med Chem (2024) 273 : 116523 -116523
PubMed 38795518 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.69 5.69

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5597242 1 5.69

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5597242 Ki = 2050.0 nM 5.69