Assay Detail
Binding
CHEMBL5585983
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human Cathepsin S assessed as inhibition constant
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel selective proline-based peptidomimetics for human cathepsin K inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.10 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4761511 | — | — | 1 | 7.10 |
| CHEMBL5598296 | — | — | 1 | 5.10 |
| CHEMBL5597902 | — | — | 1 | - |
| CHEMBL5598028 | — | — | 1 | - |
| CHEMBL5596746 | — | — | 1 | - |
| CHEMBL5596423 | — | — | 1 | - |
| CHEMBL5597252 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4761511 | — | Ki | = | 79.43 | nM | 7.10 |
| CHEMBL5598296 | — | Ki | = | 7943.28 | nM | 5.10 |
| CHEMBL5597902 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL5598028 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL5596746 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL5596423 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL5597252 | — | Ki | > | 100000.0 | nM | - |