Assay Detail
Binding
CHEMBL5586191
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Inhibition of mushroom tyrosinase monophenolase activity
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Molecular understanding of the therapeutic potential of melanin inhibiting natural products.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.88 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL382408 | PENTAGALLOYL GLUCOSE | — | 1 | 7.70 |
| CHEMBL311498 | CIANIDANOL | 4.0 | 1 | 7.22 |
| CHEMBL5597632 | — | — | 1 | 6.77 |
| CHEMBL288114 | GALLIC ACID | 2.0 | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL382408 | PENTAGALLOYL GLUCOSE | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL311498 | CIANIDANOL | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL5597632 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL288114 | GALLIC ACID | IC50 | = | 1530.0 | nM | 5.82 |