Assay Detail
Binding
CHEMBL5587766
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Inhibition of ATM (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small Molecular Inhibitors That Target ATM for Drug Discovery: Current Research and Potential Prospective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.77 | 8.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5419324 | — | — | 1 | 8.94 |
| CHEMBL5596626 | — | — | 1 | 8.15 |
| CHEMBL5597386 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5419324 | — | IC50 | = | 1.15 | nM | 8.94 |
| CHEMBL5596626 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL5597386 | — | IC50 | = | 600.0 | nM | 6.22 |