Assay Detail
Binding
CHEMBL5587776
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to METTL3 (unknown origin) assessed as dissociation constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
N6-adenosine-methyltransferase catalytic subunit (CHEMBL4739695) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Methyl-Transferase-Like Protein 16 (METTL16): The Intriguing Journey of a Key Epitranscriptomic Player Becoming an Emerging Biological Target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.52 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5597626 | — | — | 1 | 5.55 |
| CHEMBL74689 | PHENYL(METHYL)THIOSEMICARBAZONE | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5597626 | — | Kd | = | 2840.0 | nM | 5.55 |
| CHEMBL74689 | PHENYL(METHYL)THIOSEMICARBAZONE | Kd | = | 3310.0 | nM | 5.48 |