Assay Detail
Binding
CHEMBL5608455
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDE7A (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A (CHEMBL3012) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Opportunities and perspectives of small molecular phosphodiesterase inhibitors in neurodegenerative diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.97 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL484928 | — | — | 1 | 6.82 |
| CHEMBL5612937 | — | — | 1 | 5.94 |
| CHEMBL5613951 | — | — | 1 | 5.80 |
| CHEMBL451589 | — | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL484928 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL5612937 | — | IC50 | = | 1150.0 | nM | 5.94 |
| CHEMBL5613951 | — | IC50 | = | 1590.0 | nM | 5.80 |
| CHEMBL451589 | — | IC50 | = | 4700.0 | nM | 5.33 |