Compound Detail
CHEMBL5612937
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Basic Information
| ChEMBL ID | CHEMBL5612937 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BNFQSNOQIMFAIQ-QLYXXIJNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
416.5
MW (Da)
3.85
ALogP
7
HBA
1
HBD
82.5
PSA (Ų)
0.17
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.94
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| High affinity 3',5'-cyclic-AMP phosphodiesterase 7A CHEMBL3012 | IC50 | 5.94 | 5.94 | 1150.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| High affinity 3',5'-cyclic-AMP phosphodiesterase 7A | IC50 | = | 1150.0 | nM | 5.94 | Inhibition of PDE7A (unknown origin) | 38614063 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38614063 | 10.1016/j.ejmech.2024.116386 | High affinity 3',5'-cyclic-AMP phosphodiesterase 7A | 1 |
Data from ChEMBL 36 via Core Engine