Assay Detail
Functional
CHEMBL5608635
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Development and therapeutic perspectives of CXCR4 antagonists for disease therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.13 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4568686 | — | — | 1 | 7.40 |
| CHEMBL4548792 | — | — | 1 | 7.40 |
| CHEMBL4529751 | — | — | 1 | 6.96 |
| CHEMBL4451705 | — | — | 1 | 6.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4568686 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL4548792 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL4529751 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL4451705 | — | EC50 | = | 170.0 | nM | 6.77 |