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Assay Detail

CHEMBL5608665

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Functional
Antiproliferative activity against human HL-60 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Structural modification strategies of triazoles in anticancer drug development.
Guan Q, Gao Z, Chen Y, Guo C, Chen Y, Sun H.
Eur J Med Chem (2024) 275 : 116578 -116578
PubMed 38889607 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.63 5.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL488644 1 5.68
CHEMBL5613566 1 5.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL488644 IC50 = 2070.0 nM 5.68
CHEMBL5613566 IC50 = 2720.0 nM 5.57