Assay Detail
Binding
CHEMBL5610318
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FABP4 (unknown origin) incubated for 3 mins by fluorescence based analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Fatty acid-binding protein, adipocyte (CHEMBL2083) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Design, synthesis, and biological evaluation of novel highly selective non-carboxylic acid FABP1 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.62 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL247920 | — | — | 1 | 6.40 |
| CHEMBL5420532 | — | — | 1 | 5.25 |
| CHEMBL5396467 | — | — | 1 | 5.21 |
| CHEMBL5612524 | — | — | 1 | - |
| CHEMBL5556772 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL247920 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL5420532 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL5396467 | — | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL5612524 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL5556772 | — | IC50 | > | 15000.0 | nM | - |