Assay Detail
Binding
CHEMBL5615029
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]prazosin from recombinant human alpha 1B adrenoceptor extracted from CHO cell membrane incubated for 60 mins by radioligand binding assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of MT-1207: A Novel, Potent Multitarget Inhibitor as a Promising Clinical Candidate for the Treatment of Hypertension.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.82 | 9.82 |
| Ki | 1 | 10.07 | 10.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5618291 | — | — | 2 | 10.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5618291 | — | Ki | = | 0.086 | nM | 10.07 |
| CHEMBL5618291 | — | IC50 | = | 0.15 | nM | 9.82 |