Assay Detail
Functional
CHEMBL5615316
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Antiviral activity against Enterovirus A71 infected in human RD cells assessed as reduction in cytopathic effect incubated for 72 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterovirus A71 |
| Cell Type | RD |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
7-Amino-3-phenyl-2-methyl-pyrazolopyrimidine derivatives inhibit human rhinovirus replication.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.43 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5619521 | — | — | 1 | 8.10 |
| CHEMBL5618151 | — | — | 1 | 7.54 |
| CHEMBL283403 | ENVIROXIME | 2.0 | 1 | 6.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5619521 | — | EC50 | = | 8.0 | nM | 8.10 |
| CHEMBL5618151 | — | EC50 | = | 29.0 | nM | 7.54 |
| CHEMBL283403 | ENVIROXIME | EC50 | = | 231.0 | nM | 6.64 |