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Assay Detail

CHEMBL5615717

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of SARS-CoV-2 MPro
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Replicase polyprotein 1ab (CHEMBL4523582)
Type SINGLE PROTEIN
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Thioamides in medicinal chemistry and as small molecule therapeutic agents.
Huang G, Cierpicki T, Grembecka J.
Eur J Med Chem (2024) 277 : 116732 -116732
PubMed 39106658 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.89 7.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5201264 1 7.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5201264 IC50 = 13.0 nM 7.89