Assay Detail
Functional
CHEMBL5615860
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human EP2 receptor expressed in HEK293 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Prostaglandin E2 receptor EP2 subtype (CHEMBL1881) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A comprehensive review of new small molecule drugs approved by the FDA in 2022: Advance and prospect.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.96 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4297666 | OMIDENEPAG ISOPROPYL | 4.0 | 1 | 8.96 |
| CHEMBL3707245 | OMIDENEPAG | 2.0 | 1 | 8.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4297666 | OMIDENEPAG ISOPROPYL | EC50 | = | 1.1 | nM | 8.96 |
| CHEMBL3707245 | OMIDENEPAG | EC50 | = | 1.1 | nM | 8.96 |