Assay Detail
Functional
CHEMBL5621591
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiprotozoal activity against Leishmania amazonensis axenic amastigotes assessed as growth inhibition measured after 5 days by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania amazonensis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Molecular-level strategic goals and repressors in Leishmaniasis - Integrated data to accelerate target-based heterocyclic scaffolds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.90 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13045 | CHELERYTHRINE | — | 1 | 7.52 |
| CHEMBL1187176 | — | — | 1 | 6.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13045 | CHELERYTHRINE | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL1187176 | — | IC50 | = | 540.0 | nM | 6.27 |