Compound Detail
CHEMBL1187176
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1187176 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TXASKRGBMHFMPT-UHFFFAOYSA-O |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
334.4
MW (Da)
3.41
ALogP
4
HBA
1
HBD
51.8
PSA (Ų)
0.43
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leishmania amazonensis CHEMBL612877 | IC50 | 6.27 | 6.27 | 540.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leishmania amazonensis | IC50 | = | 540.0 | nM | 6.27 | Antiprotozoal activity against Leishmania amazonensis axenic amastigotes assesse... | 37257213 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37257213 | 10.1016/j.ejmech.2023.115471 | Leishmania amazonensis | 1 |
Data from ChEMBL 36 via Core Engine