Assay Detail
Binding
CHEMBL5621734
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Inhibition of [3H]-colchicine binding to tubulin (unknown origin) at 1 uM relative to control
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Synthesis and bioevaluation of novel stilbene-based derivatives as tubulin/HDAC dual-target inhibitors with potent antitumor activities in vitro and in vivo.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.20 | 4.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5624856 | — | — | 1 | 4.27 |
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 4.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5624856 | — | IC50 | = | 53760.0 | nM | 4.27 |
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 73580.0 | nM | 4.13 |