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Assay Detail

CHEMBL5621856

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant human PDGFRbeta using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Platelet-derived growth factor receptor beta (CHEMBL1913)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Research progress of VEGFR small molecule inhibitors in ocular neovascular diseases.
Jiang D, Xu T, Zhong L, Liang Q, Hu Y, Xiao W, Shi J.
Eur J Med Chem (2023) 257 : 115535 -115535
PubMed 37285684 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.94 6.94

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4303201 CATEQUENTINIB 3.0 1 6.94

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4303201 CATEQUENTINIB IC50 = 115.0 nM 6.94